Foundation Models

Built for Scale. Engineered for Intelligence. Designed for Discovery.

Paige’s foundation models redefine what’s possible in pathology. Built on the world’s largest dataset of digitized slides, our technology captures the intricate complexities of tissue like never before—enabling new levels of discovery, precision, and performance.

Two Foundation Model Suites. Unlimited Possibilities.


Virchow: Vision AI

Virchow

The first million-slide foundation model for cancer, setting the benchmark for computational pathology

Virchow2

Expanded multi-scale training (H&E + IHC), boosting precision across 40+ tissue types

Virchow2G

Our largest model yet—1.8B parameters—optimized for high-stakes pathology AI

Virchow2G-Mini

A lightweight alternative, delivering high-throughput performance on limited compute

Virchow

Virchow2

Virchow 2G

Virchow 2G-Mini

Dataset 1.5 million H&E WSIs 3 million H&E & 400k IHC WSIs 3 million H&E & 400k IHC WSIs 3 million H&E & 400k IHC WSIs
Tissue Types 17 tissue types 40 tissue types 40 tissue types 40 tissue types
Parameters 632 million parameters 632 million parameters 1.8 billion parameters 21.6 million parameters
Magnifications 20X magnifications 5x, 10x, 20x, 40x magnifications 5x, 10x, 20x, 40x magnifications 5x, 10x, 20x, 40x magnifications
Publication Published in Nature Medicine [paper link] Arxiv Paper Arxiv Paper Arxiv Paper
Availability Hugging Face + Azure AI Foundry Hugging Face + Azure AI Foundry + Commercial License Commercial License Only Commercial License Only

PRISM: Multi-Modal AI

  • Combines Large Vision Models (LVMs) with Large Language Models (LLMs) for slide-level analysis.

  • Built using Virchow, PRISM analyzes and extracts insights from tissue at the whole slide level

  • Automated Clinical Report Generation | Converts whole-slide images into free-text pathology reports

  • Zero-Shot Cancer Classification | Detects cancer subtypes and predicts biomarkers without extensive labeled data

  • Multi-Modal Intelligence | Trained from 587K slides and 195K clinical reports to generate text-based insights

PRISM

587k H&E WSIs
16 tissue types
195,000 clinical text reports
20x magnification
Automatic clinical report generation complete with cancer detection, subtyping, and biomarker predictions
Arxiv Paper
Hugging Face + Azure AI Foundry

AI That Works for You

Faster AI Model Development

Reduce the time and cost of training from scratch

Regulatory-Grade Performance

Built with clinical excellence and compliance in mind

Available Integration

Compatible with leading digital pathology platforms

Ready to build advanced AI in pathology?